Biogenic Amines

Biogenic amines are primary amines, being produced in the metabolism by enzymatic decarboxylation of amino acids. Biogenic amines are found to be precursors of alkaloids and hormones. Furthermore they play an important role in the synthesis of coenzymes, vitamins and phospholipids. Some of these amines show strong physiological effects acting for example as neurotransmitters or in the context of an allergic reaction. We can distinguish between endogenic and exogenic biogenic amines. Whereas endogenic amines are produced in many different tissue (for example: Adrenaline in the adrenal gland or Histamine in nervous system, leucocytes and mast cells) the exogenic amines are absorbed in the gut. Interestingly alcohol can increase the absorption rate. Different enzymes can degrade biogenic amines and control their physiological effects. An excessive amount of biogenic amines in the organism can lead to headache, skin irritation, respiratory distress, gastric disorders and many other symptoms resembling a medical condition we usually find in the context of an allergic reaction.

Product

Ordering number

Tests

Sample type

Incubation

Adrenalin (Epinephrine)

ELISA High Sensitive

AMP 210-EBA E-4100

96

P

extraction and acylation 4 h EIA overnight

ELISA Fast Track

AMP 210-EBA E-6100

96

P, U

extraction and acylation 65 min EIA 3 h

ELISA Fast Track

AMP 210-EBA E-7100

96

U

extraction and acylation 60 min EIA 1 h

ELISA Research

AMP 210-EBA E-5100

96

BF

extraction, acylation and  enzym. conversion 4 h, EIA overnight

RIA High Sensitive

AMP 210-RBA R-4100

96

P

extraction and acylation 4 h RIA overnight

RIA Fast Track

AMP 210-RBA R-6100

96

P, U

extraction and acylation 65 min RIA 1,5 h

RIA Fast Track

AMP 210-RBA R-7100

96

U

extraction and acylation 65 min RIA 1,5 h

2 CAT (Adrenalin and Noradrenalin)

ELISA High Sensitive

AMP 210-EBA E-4500

2 x 96

P

extraction and acylation 4 h EIA overnight

ELISA Fast Track

AMP 210-EBA E-6500

2 x 96

P, U

extraction and acylation 65 min EIA 3 h

ELISA Fast Track

AMP 210-EBA E-7500

2 x 96

U

extraction and acylation 60 min EIA 1 h

ELISA Research

AMP 210-RBA E-5400

2 x 96

BF

extraction, acylation u. enzym. Conversion 4 h, EIA overnight

RIA High Sensitive

AMP 210-RBA R-4500

2 x 96

P

extraction and acylation 4 h RIA overnight

RIA Fast Track

AMP 210-RBA R-6500

2 x 96

P, U

extraction and acylation 65 min RIA 1,5 h

RIA Fast Track

AMP 210-RBA R-7500

2 x 96

U

extraction and acylation 65 min RIA 1,5 h

3 CAT (Adrenalin, Noradrenalin and Dopamin)

ELISA High Sensitive

AMP 210-EBA E-4600

3 x 96

P

extraction and acylation 4 h EIA overnight

ELISA Fast Track

AMP 210-EBA E-6600

3 x 96

P, U

extraction and acylation 65 min EIA 3 h

ELISA Fast Track

AMP 210-EBA E-7600

3 x 96

U

extraction and acylation 60 min EIA 1 h

ELISA Research

AMP 210-RBA E-5600

3 x 96

BF

extraction, acylation and enzym. conversion 4 h, EIA overnight

RIA High Sensitive

AMP 210-RBA R-4600

3 x 96

P

extraction and acylation 4 h RIA overnight

RIA Fast Track

AMP 210-RBA R-6600

3 x 96

P, U

extraction and acylation 65 min RIA 1,5 h

RIA Fast Track

AMP 210-RBA R-7600

3 x 96

U

extraction and acylation 65 min RIA 1,5 h

Dopamin

ELISA High Sensitive

AMP 210-EBA E-4300

96

P

extraction and acylation 4 h EIA overnight

ELISA Fast Track

AMP 210-EBA E-6300

96

P, U

extraction and acylation 65 min EIA 3 h

ELISA Fast Track

AMP 210-EBA E-7300

96

U

extraction and acylation 60 min EIA 1 h

ELISA Research

AMP 210-EBA E-5300

96

BF

extraction, acylation and enzym. conversion 4 h, EIA overnight

RIA High Sensitive

AMP 210-RBA R-4300

96

P

extraction and acylation 4 h, RIA overnight

RIA Fast Track

AMP 210-RBA R-6300

96

P, U

extraction and acylation 65 min EIA 1,5 h

RIA Fast Track

AMP 210-RBA R-7300

96

U

extraction and acylation 65 min EIA 1,5 h

GABA

ELISA

AMP 210-EBA E-2500

96

U, S, P

extraction 2,5 h, EIA overnight

Glutamat

ELISA

AMP 210-EBA E-2400

96

U

extraction 2,5 h, EIA overnight

Glycine

ELISA

AMP 210- E-2100

96

U

Sample preparation 2,5 h, ELISA overnight

Histamin

ELISA

AMP 210-EBA E-1000

96

U, P

acylation 1.5 h, EIA overnight

ELISA

AMP 210-EBA E-1700

96

CC, U, Blut

acylation 15 min, EIA 1 h

ELISA Research

AMP 210-EBA E-5800

96

BF

acylation 1.5 h, EIA overnight

Histamin, Release

ELISA

AMP 210-EBA E-1100

96

Blut

sample preparation 1.5 h, EIA overnight

Kynurenine

ELISA

AMP 210-E-2200

96

S, P

30 min

Melatonin, Direct

ELISA Research

AMP 210-EBA E-3900

96

BF

sample preparation 30 min, EIA overnight

RIA

AMP 210-RBA R-3400

96

S, P, Sa

sample preparation 2 h, RIA overnight

RIA

AMP 210-RBA R-3900

100

Blood, S

sample preparation 1 h, RIA overnight

Metanephrin Plasma

ELISA Fast Track

AMP 210-EBA E-8100

96

P

sample preparation 15 min, EIA overnight

RIA Fast Track

AMP 210-RBA R-8100

96

P

sample preparation 15 min, RIA 3.5 h or overnight

Metanephrin Urin

ELISA Fast Track

AMP 210-EBA E-8400

96

U

hydrolysis and acylation 45 min

EIA 1 h

RIA Fast Track

AMP 210-RBA R-8400

96

U

hydrolysis and acylation 45 min

RIA 1.5 h

2-MET Plasma (Metanephrin and Normetanephrin)

ELISA Fast Track

AMP 210-EBA E-8300

2 x 96

P

sample preparation 15 min, EIA overnight

RIA Fast Track

AMP 210-RBA R-8300

2 x 96

P

sample preparation 15 min, RIA 3.5 h  or overnight

2-MET Urine (Metanephrin and Normetanephrin)

ELISA Fast Track

AMP 210-EBA E-8600

2 x 96

U

hydrolysis and acylation 45 min, EIA 1 h

RIA Fast Track

AMP 210-RBA R-8600

2 x 96

U

hydrolysis and acylation 45 min, RIA 1.5 h

Noradrenalin (Norepinephrine)

ELISA High Sensitive

AMP 210-EBA E-4200

96

P

extraction and acylation 4 h, EIA overnight

ELISA Fast Track

AMP 210-EBA E-6200

96

P, U

extraction and acylation, 65 min, EIA 3 h

ELISA Fast Track

AMP 210-EBA E-7200

96

U

extraction and acylation, 60 min, EIA 1 h

ELISA Research

AMP 210-RBA E-5200

96

BF

extraction, acylation a. enzym. conversion 4 h, EIA overnight

RIA High Sensitive

AMP 210-RBA R-4200

96

P

extraction and acylation 4 h, RIA overnight

RIA Fast Track

AMP 210-RBA R-6200

96

P, U

extraction and acylation 65 min, RIA 1,5 h

RIA Fast Track

AMP 210-RBA R-7200

96

U

extraction and acylation 65 min, RIA 1,5 h

Normetanephrin Plasma

ELISA Fast Track

AMP 210-EBA E-8200

96

P

sample preparation 15 min, EIA overnight

RIA Fast Track

AMP 210-RBA R-8200

96

P

sample preparation 15 min, RIA 3.5 h or overnight

Normetanephrin Urine

ELISA Fast Track

AMP 210-EBA E-8400

96

U

hydrolysis and acylation 45 min, EIA 1 h

RIA Fast Track

AMP 210-RBA R-8400

96

U

hydrolysis and acylation 45 min, RIA 1.5 h

Serotonin

ELISA Fast Track

AMP 210-EBA E-8900

96

U, S, Thrombocytes

acylation 15 min, EIA 1 h

ELISA Research

AMP 210-EBA E-5900

96

BF

sample preparation 30 min, EIA overnight

RIA Fast Track

AMP 210-RBA R-8900

96

U, S, PEP,

PRP, CSF

acylation 30 min, RIA 2 h

Tryptophan

ELISA

AMP 210-EBA E-2700

96

S, P, U

sample preparation 2.5 h, EIA overnight

5-HIAA

ELISA

AMP 210-EBA E-1900

96

U

sample preparation 20 min, EIA 2.5 h

Food control

HistaSureTM

ELISA

AMP 210-EFC E-3100

96

Fish meal, fresh fish, milk, cheese,
sausage, wine

acylation 15 min, EIA 1 h

ELISA

AMP 210-EFC E-3600

96

Fish meal

acylation 5 min, EIA 20 min

Glutamate Food

ELISA

AMP 210-EFC E-3700

96

food

extraction 2 h, EIA 1 h