Autoimmune Diseases

Autoimmune disease describes a medical condition caused by an excessive reaction of the human immune system to body´s own structures. By mistake the immune cells take own cells as host cells causing severe inflammation and damage to the organs concerned. To enable the immune system to distinguish between „host“ and “own“ so called MHC proteins (Major Histocompatibility Complex) are expressed on every cell surface. There are two types of MHC proteins: HLA-class-I-molecules are found on every nucleus containing cell whereas HLA-class-II-molecules characterize antigen-presenting cells like macrophages. During the autoimmune response B lymphocytes produce auto-antibodies that are released into the blood. Reaching different parts of the organism they finally bind to and mark their specific antigen on a cell surface leading to destruction and phagocytosis of these cells. Actually every organ can be affected. Usually autoimmune diseases are treated symptomatically.

Product

Ordering number

Tests

Sample type

Incubation

21-Hydrolase Ab

RIA

AMP 20-R13400

50

on request

overnight, 1 h, 30 min

anti -CCP

ELISA

AMP 20-E17800

96

on request

1 h, 1 h, 30 min

anti-GAD65

ELISA

AMP 20-E3802

96

S

2 h, 30 min

ELISA

AMP 20-E6000

96

S

1 h, 1 h, 20 min, 20 min

RIA

CentAK AMP 20-R1700

100

S

3 h

anti-Gliadin IgA

ELISA

AMP 20-E12900

96

S, P

30 min, 30 min, 30 min

ELISA

AMP 20-E3700

96

S

1 h, 30 min, 15 min

anti-Gliadin IgG

ELISA

AMP 20-E12800

96

S, P

30 min, 30 min, 30 min

ELISA

AMP 20-E3800

96

S

1 h, 30 min, 15 min

anti-IA2

ELISA

AMP 20-E3803

96

S

overnight, 1 h,  20 min

RIA

AMP 20-R61100

100

S

18 h, 30 min

anti-Insulin Ab

ELISA

AMP 20-E13800

96

S, P

30 min, 15 min, 15 min, 5 min

anti-Ovarian Ab

ELISA

AMP 20-E14500

96

S

1 h, 1 h, 30 min

anti-Transglutaminase IgA

ELISA

AMP 20-E17500

96

S, P

30 min, 15 min, 15 min, 5 min

anti-Transglutaminase IgG

ELISA

AMP 20-E17600

96

S, P

30 min, 15 min, 15 min, 5 min

anti-hu TransG

ELISA

AMP 20-E4033

96

S

1 h, 30 min, 15 min

anti-hu tTg IgG

ELISA

AMP 20-E4044

96

S

1 h, 30 min, 15 min

ASCA IgA

ELISA

AMP 20-E4006

96

S

1 h, 30 min, 15 min

ASCA IgG

ELISA

AMP 20-E4007

96

S

1 h, 30 min, 15 min

GliaDea IgA

ELISA

AMP 20-E3710

96

S

1 h, 30 min, 15 min

GliaDea IgG

ELISA

AMP 20-E3810

96

S

1 h, 30 min, 15 min

Insulin Autoantibody (IAA)

ELISA

AMP 20-E13500

96

S

30 min, 15 min, 15 min, 5 min

Intra-Cell Autoantibody (ICA)

ELISA

AMP 20-E13700

96

S

1 h, 1 h, 30 min

Phosphatidyl Serin Ab IgG, IgM

ELISA

AMP 20-E15900

96

S, P

30 min, 15 min, 15 min, 5 min

Rheumatoid Factor IgA

ELISA

AMP 20-E15700

96

S, P

30 min, 15 min, 15 min, 5 min

Rheumatoid Factor IgG

ELISA

AMP 20-E15600

96

S, P

30 min, 15 min, 15 min, 5 min

Rheumatoid Factor IgM

ELISA

AMP 20-E15800

96

S, P

30 min, 15 min, 15 min, 5 min

Rheumatoid Factor Screen

ELISA

AMP 20-E15500

96

S, P

30 min, 15 min, 15 min, 5 min

Sperm Antibody

ELISA

AMP 30-E4900

96

S

1 h, 1 h, 30 min

Thyroglobulin Ab (TG Ab)

ELISA

AMP 20-E17100

96

S, P

1 h, 1 h, 15 min

RIA

Selco anti-TG AMP 90-R1540

100

S

2 h

Thyroid Peroxidase Ab (TPO Ab)

ELISA

Anti-TPO AMP 90-E3002

96

S, P

1 h, 30 min, 15 min

RIA

Anti-TPO AMP 90-R1500

100

S

1,5 h

TSH Receptor Ab

ELISA

AMP 20-E4003

96

S

2 h, 20 min, 20 min, 20 min

RIA CT

TRAB AM'P 90-R1040

100

S

2 h, 1 h

Tissue Transglutaminase IgA

ELISA

AMP 20-E17700

96

S

30 min, 30 min, 30 min

Tissue Transglutaminase IgG

ELISA

AMP 20-E17900

96

S

30 min, 30 min, 30 min