Herpes Virus Infections

Cytomegalievirus (CMV)

Cytomegalovirus (CMV) is a double-stranded DNA virus and a member of the Herpesviridae family. This family also includes herpes simplex virus type 1 (HSV-1 or HHV-1) and herpes simplex virus type 2 (HSV-2 or HHV-2), varicella zoster virus (VZV), human herpesvirus (HHV)–6, HHV-7, and HHV-8. CMV shares many attributes with other herpes viruses, including genome, virion structure, and the ability to cause latent and persistent infections. Human CMV grows only in human cells and replicates best in human fibroblasts. About 58.9% of individuals aged 6 and over are infected with CMV while 90.8% of individuals aged 80 and over are positive for CMV antibodies. Symptomatic CMV disease in immunocompromised individuals can affect almost every organ of the body, resulting in fever, pneumonia, hepatitis, encephalitis, myelitis, colitis, uveitis, retinitis, and neuropathy. In patients coinfected with HIV, CMV infection leads to progression to AIDS and eventually death, even in those receiving highly active antiretroviral therapy (HAART).

CMV kits

V7-100FRT

SA, RG, iQ, SC,MX, A,IL,B,LC

CMV Real-TM

Real Time Amplification kit

R

CE1023

100

5 х102 copies/ml

V7-100/2FRT

SA, RG, iQ, SC,MX, A,IL,B

CMV Real-TM Quant

Real Time PCR kit with the DNA extraction controls

R

CE1023

100

2 х102 copies/ml

V48-100FRT

SA, RG, iQ, SC,MX, A

CMV/EBV/HHV6 Real-TM Quant

Real Time Amplification kit

R

CE1023

100

2 х102 copies/ml

Herpes simplex

Herpes simplex is a viral disease caused by both herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). Infection with herpes virus is categorized into one of several distinct disorders based on the site of infection. Oral herpes, the visible symptoms of which are colloquially called cold sores or fever blisters, infects face and mouth. Oral herpes is the most common form of infection. Genital herpes, known simply as herpes, is the second most common form of herpes. Other disorders such as herpetic whitlow, herpes gladiatorum, ocular herpes (keratitis), cerebral herpes infection encephalitis, Mollaret’s meningitis, neonatal herpes, and possibly Bell’s palsy are all caused by herpes simplex viruses. Varicella zoster virus (VZV) is known to infect humans (and other vertebrates) and commonly causes chicken-pox in children.

Herpes simplex kits

TV8-100FRT

SA, RG, iQ, SC,MX, A,IL,B,LC

HSV 1/2 Real-TM

Complete Real Time Test with DNA-Sorb-A extraction kit

R

CE

100

5 х102 copies/ml

V8-100FRT

SA, RG, iQ, SC,MX, A,IL,B,LC

HSV 1/2 Real-TM

Real Time Amplification kit

R

CE

100

5 х102 copies/ml

TV38-100FRT

SA, RG, iQ, MX, SC, A,IL,B

HSV 1/2 Typing Real-TM

Complete Real Time Test with DNA-Sorb-A extraction kit

R

CE

100

5 х102 copies/ml

V38-100FRT

SA, RG, iQ, SC,MX, A,IL,B

HSV 1/2 Typing Real-TM

Real Time Amplification kit

R

CE

100

5 х102 copies/ml

V60-100FRT

SA, RG, iQ, SC,MX, A,IL,B

HSV/CMV Screen Real-TM

Real Time Amplification kit

R

CE1023

100

5 х102 copies/ml

TV61-50FRT

SA, RG, iQ, SC,MX, A,IL,B

VZV Real-TM

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

100

5 х102 copies/ml

V61-50FRT

SA, RG, iQ, SC,MX, A,IL,B

VZV Real-TM

Real Time Amplification kit

R

CE

50

5 х102 copies/ml

V-8-100R

HSV 430/720 IC

A

CE

110

1 х103 copies/ml

Epstein-Barr virus (EBV)

Epstein-Barr virus (EBV), or human herpesvirus 4, is a gamma herpesvirus that is found in more than 95% of the world’s population. The most common manifestation of primary infection by this organism is acute infectious mononucleosis, a self-limited clinical syndrome that most frequently affects adolescents and young adults. Classic symptoms include sore throat, fever, and lymphadenopathy. However, Epstein-Barr virus is also a tumor virus, associated with human malignancy (nasopharyngeal carcinoma and Burkitt lymphoma).

EBV kits

TV9-50FRT

SA, RG, iQ, SC,MX, A,IL,B

EBV Real-TM Quant

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

50

2 х102 copies/ml

V9-50FRT

SA, RG, iQ, SC,MX, A,IL,B

EBV Real-TM Quant

Real Time Amplification kit with the DNA extraction controls

R

CE

50

2 х102 copies/ml

 

TV9-100FRT

SA, RG, iQ, SC,MX, A,IL,B

EBV Real-TM Quant

Complete Real Time Test with DNA-Sorb-B extraction kit

R  CE  100  2 х102 copies/ml 

V9-100FRT

SA, RG, iQ, SC,MX, A,IL,B

EBV Real-TM Quant

Real Time Amplification kit with the DNA extraction controls

R  CE  100  2 х102 copies/ml 

V-9-100R

EBV 290

A

 CE

110

5 х102 copies/ml

Human Herpes Virus 6 (HHV6)

Human herpesvirus 6 (HHV-6)was the sixth herpesvirus discovered. Isolated in 1986 during attempts to find novel viruses in patients with lymphoproliferative diseases, HHV-6 is now recognized as a T-cell lymphotrophic virus with high affinity for CD4 lymphocytes. As a beta herpesvirus (like cytomegalovirus [CMV] and human herpesvirus type 7), HHV-6 has two variants, A and B. HHV-6B causes the childhood illness roseola infantum, while HHV-6A has been isolated mainly in immunocompromised hosts. HHV-6 also has been implicated in the pathogenesis of white-matter demyelination in persons with AIDS dementia complex; however, causality has not been proven. HHV-6 has been isolated from various tissues, cells, and fluids in association with the following conditions: Kikuchi lymphadenitis, Lymphoma, Lymphadenopathy, Sjögren syndrome, Sarcoidosis, Systemic lupus erythematosus, Guillain-Barré syndrome, Multiple sclerosis.

HHV-6

TV10-100FRT

SA, RG, iQ, SC,MX, A,IL,B

HHV6 Real-TM Quant

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

100

2 х102 copies/ml

V10-100FRT

SA, RG, iQ, SC,MX, A,IL,B

HHV6 Real-TM Quant

Real Time Amplification kit

R

CE

100

2 х102 copies/ml