Hepatitis Viruses

Hepatitis is an infectious liver disease caused by hepatotropic viruses belonging to different families. There are 5 major viruses that cause hepatitis. They make up two groups of hepatitis: enteric (HAV and HEV) and parenteral (HBV, HCV and HDV).

Hepatitis A (HAV)

Hepatitis A is the enteric infection most widely spread in the world. It is an acute infectious disease of liver transmitted by fecal-oral way, the causative agent of which is hepatitis A virus (HAV) belonging to the family Picornaviridae. Virus hepatitis A is one of the five most economically significant infectious diseases and one of the priority problems of public healthcare.Detection of the causative agent RNA by PCR method has significant advantages compared to ELISA and biochemical tests. RNA of the hepatitis A virus appears in the blood on the third week from the moment of contamination and is detected at the average within 20 days after appearance of the first symptoms. Thus, RNA is the first diagnostic marker detected in the patient blood occuring earlier than IgM antibodies without giving false negative reactions.

Hepatitis A Virus kits

TV4-50FRT

SA, RG, iQ, SC,MX, A, IL, B, LC

HAV Real-TM Qual

Complete Real Time Test with Ribo-Sorbextraction kit

R

CE

50

5 х 102 copies/ml

TV4-50FRT C

SA, RG, iQ, SC,MX, A, IL, B, LC

HAV Real-TM Qual

Complete Real Time Test with Ribo-Virus column extraction kit

R

CE

50

5 х 102 copies/ml

 

V4-50FRT

SA, RG, iQ, SC,MX, A, IL, B, LC

HAV Real-TM Qual

Real Time Amplification kit with RNA extraction controls

R

CE

50

5 х 102 copies/ml

 

Hepatitis B (HBV)

Hepatitis В is a widely spread human infection caused by DNA-containing hepatitis В virus (HBV). Transmission results from exposure to infectious blood or body fluids. Possible forms of transmission include unprotected sexual contact, blood transfusions, re-use of contaminated needles & syringes, and vertical transmission from mother to child during childbirth. The viral hepatitis B presents a serious problem for public healthcare due to its universal spread. At present the population infected with HBV  makes 500 million people. Detection of HBV DNA is used for:

• Early diagnostic of acute viral hepatitis В

• Detection of latent forms of viral hepatitis В

• Detection of mutant strains of hepatitis В virus by HBsAg

• Assessment of chronic viral hepatitis В

• Monitoring the effectiveness of antiviral therapy

Hepatitis B Virus kits

V5-96/3FRT

SA, RG

HBV Real-TM Quant DX NEW

Real Time Amplification kit with positive controls and standards, 96 ready to use lyophilized PCR tubes

R

CE1023

96

Linearity:

7 - 108

IU/ml

 

Hepatitis C (HCV) and Hepatitis G (HGV)

Hepatitis С virus (HCV) is a RNA-containing, hepatotropic virus belonging to the Flaviviridae family. Contamination with hepatitis С virus occurs at direct entering of the virus in blood (at parenteral interventions or during blood transfusions). Most people with acute HCV infection are asymptomatic or have mild symptoms (fatigue, nausea, jaundice) but they are unable to clear the virus and in approximately 80% of cases, this leads to chronic infection. In 15 to 20% of patients chronic HCV infection progresses to cirrhosis, with a 1 to 4% annual risk of developing hepatocellular carcinoma.

Hepatitis C Virus kits

V1-96/3FRT

SA, RG

 

HCV Real-TM Quant DX NEW

Real Time Amplification kit with positive controls and

standards, 96 ready to use lyophilized PCR tubes

R

CE1023

96

Linearity:

13 - 108

IU/ml

 HCV associated kits

R05-100FRT

SA, RG, iQ, MX, A, B

Il28B rs17/rs60 Real-TM

Real Time Amplification kit

R

CE

100

Hepatitis G Virus kits

TV20-50FRT

SA, RG, iQ, SC, MX, A, IL, B, LC

HGV Real-TM

Real Time PCR kit with Ribo-Sorb extraction kit

R

CE

50

5 x 102 copies/ml

V20-50FRT

SA, RG, iQ, SC, MX, A, IL, B, LC

HGV Real-TM

Real Time PCR kit with DNA extraction controls

R CE
50

3 x 102 copies/ml