Dangerous Infections

Lyme disease

Lyme disease (LD) is a vector-borne, multisystem inflammatory disease caused by the spirochete Borrelia burgdorferi sensu lato. It is transmitted to humans by infected ticks of the Ixodes genus. After entering thecirculation, the organism invades the cutaneous, synovial, cardiac, and nervous systems. Spirochetes havealso been demonstrated histologically in bone marrow, spleen, lymph nodes, liver, testes, and placentaduring early hematogenous dissemination.

Borrelia burgdorferi kits

TB37-50FRT

SA, RG, iQ, SC, MX, A, B

Borrelia burgdorferi sensu lato Real-TM

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

50

1 х 103 copies/ml

B37-50FRT

SA, RG, iQ, SC, MX, A, B

Borrelia burgdorferi sensu lato Real-TM

Real Time Amplification kit

R

CE

50

1 х 103 copies/ml

Brucellosis

Brucellosisis a worldwide zoonosis caused by infection with the bacterial genus Brucella. These organisms, which are small aerobic intracellular coccobacilli, localize in the reproductive organs of host animals, causing abortions and sterility. They are shed in large numbers in the animal’s urine, milk, placental fluid, and other fluids. Exposure to infected animals and animal products causes brucellosis in humans. The global burden of human brucellosis remains enormous; it causes more than 500,000 infections per year worldwide. Among the 4 Brucella species known to cause disease in humans (B. abortus, B. melitensis, B. canis, B. suis), B. melitensis is thought to be the most virulent and causes the most severe and acute cases of brucellosis.

Brucella kits

TB10-50FRT

SA, RG, iQ, B

Brucella Real-TM

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

50

1 х103 copies/ml

B10-50FRT

SA, RG, iQ, B

Brucella Real-TM

Real Time Amplification kit

R

CE

50

1 х103 copies/ml

Dengue virus

This mosquito-borne single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus causes dengue fever. Four serotypes can cause the full spectrum of disease. There are not yet any vaccines to prevent infection with dengue virus and the most effective protective measures are those that avoid mosquito bites. After infection, early recognition and prompt supportive treatment can substantially lower the risk of developing severe disease.

Dengue kits

V63-G-50FRT

SA, RG, A, iQ, MX, SC, B

Dengue genotype Real-TM

Real Time Amplification kit for detection and differentiation

of Dengue genotypes 1, 2, 3 and 4

R

CE

50

5 х 102 copies/ml

V63-S-50FRT

 

Dengue Real-TM NEW

Real Time PCR kit for detection of Dengue virus

R

 CE

50

5 х 102 copies/ml

Pestis

Yersinia pestisis a gram-negative rod-shaped bacterium. It is facultative anaerobe and able to infect humans and animals. A lot of evidence suggests that it was a contributing factor in many plagues throughout human history. The reservoirs commonly associated with Y. pestisare several species of rodents (marmot, rats).

Pestis kits

B79-50FRT

SA, RG, iQ, SC, MX, A, B

Yersinia pestis

R

CE

50

5 х 103 copies/ml

Bacillus anthracis

Bacillus anthracisis a gram-positive spore-forming, rod-shaped bacterium, with a width of 1-1.2μm and a length of 3-5μm. Three forms of anthrax disease are recognized based on their form of inoculation: Cutaneous - the most common form (95%), causes a localized inflammatory black necrotic lesion (eschar), Pulmonary – highly fatal and characterized by sudden massive chest edema followed by cardiovascular shock, Gastrointestinal - rare but also fatal (mortalitiy rate  25%) type results from ingestion of spores.

Bacillus anthracis kits

TB101-50FRT

RG, iQ, SA, B

Bacillus anthracis Real-TM

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

50

5 х 102 copies/ml

B101-50FRT

RG, iQ, SA, B

Bacillus anthracis Real-TM

Real Time Amplification kit

R

CE

50

5 х 102 copies/ml

Leptospira

Leptospirosis is a worldwide zoonosis caused by pathogenic species of Leptospira. In 90% of cases, leptospirosis manifests as an acute febrile illness with a biphasic course. Nonspecific symptoms of leptospirosis (e.g., fever, headache, nausea, vomiting) can be confused with viral illness. In 10% of cases, the presentation is more dramatic, and the infection has a mortality rate of 10%. Known as Weil disease or icteric leptospirosis, the classic form of leptospirosis includes fever, jaundice, renal failure, and hemorrhage.

Leptospirosis kits

TB49-50FRT

SA, RG, iQ, SC, MX, A, B

Leptospira 16s RNA Real-TM

Complete Real Time Test with DNA-Sorb-B extraction kit

R

CE

50

1 х 103 copies/ml

B49-50FRT

SA, RG, iQ, SC, MX, A, B

Leptospira 16s RNA Real-TM

Real Time Amplification kit

R

CE

50

1 х 103 copies/ml

Congo Crimea

Congo-Crimea hemorrhagic fever is a widespread tick-borne viral disease, a zoonosis of animals that may affect humans. The pathogenic virus, commonly present in East and West Africa, is a member of the Bunyaviridae family of RNA viruses. Clinical symptoms are rare in infected mammals, but commonly severe in infected humans, with a 30% mortality rate.

Congo Crimea kits

V22-50FRT

SA, RG, iQ, SC, LC, IL, MX, A, B

Congo Crimea Real-TM

Real Time Amplification kit

R

CE

50

1 х 103 copies/ml

Tick-borne diseases

Ticks are arachnids that survive by eating blood from their hosts. They can pass infections from one host to another, including humans. Common tick-borne diseases are: Tick-Borne Encephalitis (TBE), Anaplasmosis, Ehrlichiosis.

TBEV kits

V59-100FRT

SA, RG, iQ, SC, MX, A, B

TBEV, B.burgdorferi, A.phagocytophilum, E.chaffeensis / E.muris Real-TM

Real Time Amplification kit

R

CE

100

1 х 103 copies/ml

West Nile Virus

West Nile virus belongs to the genus Flavivirus. The life cycle of this virus involves a transmission from animals to humans by way of Aedes, Culex, or Anopheles mosquitoes. The West Nile virus can infect horses, birds, dogs, and other mammals and cause serious manifestations in approximately 1% of infected persons, with increased morbidity and mortality in individuals older than 50 years. In hospitalized patients, neurologic sequelae included severe muscle weakness, with approximately 10% of patients developing a complete flaccid paralysis. One in 150 West Nile virus infections results in encephalitis or meningitis, and the mortality rate from severe illness is 3-15%.

West Nile Virus kits

TV53-50FRT

SA, RG, iQ, SC, MX, A, B

West Nile Virus Real-TM

Complete Real Time Test with Ribo-Sorb extraction kit

R

CE

50

5 х 102 copies/ml

V53-50FRT

SA, RG, iQ, SC, MX, A, B

West Nile Virus Real-TM

Real Time Amplification kit

R

CE

50

5 х 102 copies/ml

Coxiella burnetii

Q fever is a zoonosis caused by Coxiella burnetii, an obligate gram-negative intracellular bacterium. Most commonly reported in southern France and Australia, Q fever occurs worldwide. C. burnetiiinfects various hosts, including humans, ruminants (cattle, sheep, goats), and pets. In rare cases, C. burnetii infection in reptiles, birds, and ticks has been reported. C. burnetiiis excreted in urine, milk, feces, and birth products. These products, especially the latter, contain large numbers of bacteria that become aerosolized after drying. The bacterium is highly infectious.

Coxiella burnetii kits

B85-50FRT

SA, RG, iQ, SC, MX, A, B

Coxiella burnetii Real-TM

Real Time Amplification kit

R

CE

50

1 х 103 copies/ml

Bacterial pyogenic infections

Streptococcus pyogenesand Staphylococcus aureus infections are characterized by pus production (pyogenic) and the release of leukocidins that can destroy macrophages..

Bacterial pyogenic infections kits

TB77-100FRT

SA, RG, MX, iQ, SC, A, B

Streptococcus B Real-TM Quant

Complete Real Time Test with DNA/RNA Prep extraction kit

R

CE

100

300 copies/ml

B77-100FRT

SA, RG, MX, iQ, SC, A, B

Streptococcus B Real-TM Quant

Real Time Amplification kit

R

CE

100

300 copies/ml

TB82-100FRT

SA, RG, MX, iQ, SC, A, B

Streptococcus pyogenes Real-TM Quant 

Complete Real Time Test with DNA/RNA Prep extraction kit

CE  100  300 copies/ml 

B82-100FRT

SA, RG, MX, iQ, SC, A, B

Streptococcus pyogenes Real-TM Quant

Real Time Amplification kit

R

CE

100

300 copies/ml

B76-50FRT

SA, RG, MX, iQ, SC, A, B

Pseudomonas aeruginosa Real-TM Quant

Real Time Amplification kit

R

CE

50

500 copies/ml

 Bacterial Drug resistance

The term “drug resistance” is used in the context of resistance that pathogens have “acquired”. When a microorganism is resistant to more than one drug, it is said to be multidrug-resistant (MDR). Resistance to β-lactam antibiotics which include penicillins and cephalosporins make it difficult to treat with standard antibiotics.

B78-100FRT

SA, RG, MX, iQ, SC, A, B

MRSA Real-TM

Real Time Amplification kit

R

CE

100

400 copies/ml

C1-100FRT

SA, RG, A, B

MDR MBL (VIM, IMP, NDM) Real-TM

Real Time Amplification kit for etection of genes VIM, IMP, NDM in Enterobacteriaceae and NFGNB

R

CE

100

500 - 105 copies/ml

C2-100FRT

SA, RG, A, B

MDR KPC/OXA Real-TM

Real Time Amplification kit for detection of genes KPC, OXA-48, OXA-162 in Enterobacteriaceae and NFGNB

R

CE

50

500 - 105 copies/ml